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ehat is glp 1 GLP-1 vs. GLP-1 + GIP: What's the Difference for your Metabolism? GLP-1 Weight Loss Options |
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Frontiers in Pharmacology, 16 , 1572197

[DOI] [Google Scholar] 21.Montecinos K., Kania B., Goldberg D.J

N Engl J Med 358(6):580591 Garvey WT, Van Gaal L, Leiter LA, Vijapurkar U, List J, Cuddihy R et al (2018) Effects of canagliflozin versus glimepiride on adipokines and inflammatory biomarkers in type 2 diabetes

All that remains to be seen, and an absolute benefit of 1.5 per 100 people treated is certainly nothing to write home about

Other studies have reported effects on overall growth of the pancreas (as opposed to islet growth) or evidence of increased exocrine mitogenesis

In rodents [660,761] and humans [663,763], GLP-1R agonism increases renal lithium clearance, a marker for proximal tubular sodium reabsorption
