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When taken 2 hours prior to aspirin, ibuprofen interferes with aspirin's ability to inhibit the production of thromboxane A2, whereas if ibuprofen is taken 2 hours after aspirin, aspirin's antiplatelet effects are preserved (Catella-Lawson et al, 2001)

A metabolomics-based molecular pathway analysis of how the sodium-glucose co-transporter-2 inhibitor dapagliflozin may slow kidney function decline in patients with diabetes

Despite this, there was no association between the duration of treatment and the dose administered

10.1016/j.cmet.2021.01.015
