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Currently, there is an ongoing randomised double-masked placebo-controlled trial, the SUMMIT trial, studying the efficacy and safety of tirzepatide, a dual agonist of glucose-dependent insulinotropic polypeptide and GLP-1 receptors, versus placebo in HFpEF patients with obesity (NCT04847557)

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Newland-Jones adds that a balance needs to be struck between utilising these medicines for the significant benefits in all those that meet trial entry criteria and the budgetary constraints were currently in