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Completion of the trials main phase is expected in September 2025, and the 52-week extension (in which participants and investigators remain blinded to treatment assignment) will continue to October 2026

Some signs to look out for: Bloating, indigestion, or heartburn Digestive discomforts, such as gas or cramping Irregular or sluggish bowel movements Low energy or poor nutrient absorption It is also important to note that if these symptoms are persistent, painful and impacting daily life, speak to your GP or a health professional

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When to stop Mounjaro before surgery: UK guidance on managing tirzepatide perioperatively

Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1 RAs) are useful tools for treating type 2 diabetes mellitus