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NCBI PMC

GLP-1RAs modulated alcohol-induced behavior by activating GLP-1Rs in reward-related areas and in the hindbrain

The literature study demonstrates the utilization of botanical and plant-derived treatments for the management of type 2 diabetes mellitus

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This effect supports the functional role of endogenous GLP-1-containing neural pathways as mediators of aversive behaviors in rats [176]

These medications are synthetic analogs or mimetics of human GLP-1 that resist degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), allowing for prolonged therapeutic action