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The SURPASS-5 study assessed the efficacy and safety of an injectable combination therapy combining tirzepatide with insulin glargine (75)

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This is attributed to its unique triple-agonist mechanism

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Cardiovascular Protection Research has found that even at lower doses, GLP-1 agonists help lower blood pressure, improve lipid profiles by reducing LDL cholesterol and triglycerides, and reduce the risk of cardiovascular events