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This strategy becomes especially important during the dose escalation phase

The expanding role of GLP-1 receptor agonists: metabolic, cardiovascular and anti-inflammatory benefits

Nov 2022;37(14):3653-3662

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Its pharmacological actions on glucose metabolism involve the LKB1-AMPK pathway, which appears to activate ataxia-telangiectasia mutants and activation-induced cytidine deaminase (ATM) [20]
