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Description
Hormonal fluctuations disrupt leptin and ghrelin, the hormones controlling hunger and satiety
The molecule was selected for clinical development on the basis of this balanced profile and the downstream glycaemic and weight-related endpoints in the discovery programme
However, none of these findings are currently definite
2-year efficacy and safety of linagliptin compared with glimepiride in patients with type 2 diabetes inadequately controlled on metformin: a randomised, double-blind, non-inferiority trial
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Limited Weight Loss from Staying on Low Doses The importance of proper dose titration cannot be overstated, yet many patients remain on low doses, limiting their weight loss results
