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Myth 6: All GLP-1 Medications Are the Same Its easy to assume that all GLP-1 medications work the same way, but there are important differences that set them apart

Ninety-eight patients with obesity and MASLD (defined as 10% liver fat by MRI-PDFF) were contained in this substudy

Liraglutide had a similar effect but to a slightly lesser extent, which the authors attribute to differences in doses and treatment approach of the two drugs

Tate M, Robinson E, Green BD, et al

Of note, the 2022 study [19] was initially identified in our literature search as a 2021 conference abstract and was subsequently published in a journal during preparation of a revision of our manuscript

1 In one placebo-controlled trial with semaglutide (Trial to Evaluate Cardiovascular and Other Long-term Outcomes with Semaglutide in Subjects with Type 2 Diabetes [SUSTAIN 6]), 10 there was a significant early increase in diabetic retinopathy in patients allocated active therapy, which has been attributed to the rapidity and magnitude of improved glycaemic control (as has been observed in previous studies involving intensive insulin treatment) rather than being a direct adverse drug effect