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The primary outcome was new onset hypersomnolence with secondary outcomes including parasomnia, narcolepsy/cataplexy, disturbed sleep, restless legs syndrome, iron deficiency, and Parkinsonism

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For most people, a healthy calorie deficit is around 300500 calories per day

doi: 10.2741/482 68 de la MonteSMTongM

Ultimately, it allowed what should be a beneficial medication to be used in a way that could be particularly harmful, both mentally and physically

Finally, libraries were pooled and sequenced (Illumina Nextseq 500, 20 55 bp)