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You should take them when your tummy is empty

Roche's public obesity strategy, as of April 2026, centers on CT-388 (a GLP-1/GIP dual acquired through the Carmot Therapeutics acquisition) and a deep orforglipron-competitor oral GLP-1 program

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Your healthcare provider should start you at the lowest available dose and increase it slowly over time

You have a concrete plan for transitioning off the medication after 12 weeks to maintain your results

The primary objective of STEP 4 was to compare the effect of a semaglutide SC 2.4 mg injection once weekly versus placebo as an adjunct to a reduced-calorie diet and increased physical activity in patients with overweight or obesity who have reached the target dosage of semaglutide during the run-in period on body weight