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In a head-to-head trial, participants using Zepbound achieved an average weight loss of approximately 20.2% over 72 weeks, while those on Wegovy experienced about a 13.7% reduction

Nutritional adequacy requires attention, as very-low-carbohydrate diets restrict many nutrient-dense foods including fruits, whole grains, and legumes

Extremely obese persons may have as many as four times of adipocytes, than healthy controls, each obese subject containing twice as much lipids, as a lean person

Individual response varies enormously

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doi: 10.1007/s00125-009-1532-3