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However, according to data nausea, vomiting, diarrhea, and constipation affect 40%70% of patients on GLP-1 medications
[PubMed ID: 29773502]
While endogenous GLP-1 has a short half-life and limited ability to act on distant organs, exogenous GLP-1R agonists have proven highly effective in reducing food intake and promoting weight loss
Agonistas duales de receptores GLP-1 y GIP en la diabetes tipo 2: mecanismos de accin y bases fisiopatolgicas
1A) (overall P value = 0.7442, two-way ANOVA with repeated measures)
Accessed on 27th Nov 2023, Available from: Iepsen EW, Torekov SS, Holst JJ
