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Tips for a Better Experience If you choose to consume THC while on a GLP-1, a few mindful adjustments can make a big difference: Start low and go slower than usual Especially with edibles, consider reducing your typical dose

She could barely stomach more than a few bites of food

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When caloric intake drops significantly, the resulting energy deficit can manifest as fatigue, weakness, or reduced exercise tolerance

This allows the consumer to participate in the category without the immediate physical penalty of heaviness. 2

In one study, it was demonstrated that exendin-4 prevented LPS-induced depressive-like symptoms in rats and displayed antidepressant-like properties measured in the forced swim test, but this effect was not mediated by the modulation of neuroinflammatory processes, since the levels of IL-1 and TNF- were not affected by exendin-4 treatment [67]