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Stopping the medication causes appetite to return quickly, often leading to rapid weight regain and loss of the metabolic benefits

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Thus, in order to have GLP/GIP analogs with lasting effects, alterations of the peptides needed to be made in order to prevent their rapid metabolism by DPP-4 and oral administration could not be used

The difference between vial and pen storage primarily relates to air exposure: vials with unused doses can be re-capped and re-refrigerated between uses, while pens are single-use devices that must be discarded once opened, even if medication remains

These are all carbohydrate-dominant foods

Dose escalation periods : Mounjaro is typically increased in 2.5 mg increments every 4 weeks, up to a maximum of 15 mg weekly, as per the UK prescribing information