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Description
PUF-8 and GLD-2 have opposite biochemical and biological functions

GLP-1s are medications that mimic a natural hormone

Comparable conclusions were reached based on the data from the Look AHEAD randomized intensive lifestyle intervention trial that metformin provided minimal additional benefit (204)
These drugs have led to greater weight loss in clinical trials and real-world settings than orlistat, which until recently was the only drug approved for treating obesity in the European Union

Mabilleau, G., Mieczkowska, A

Table 2 gives an overview of the characteristics and results of the entire SURPASS study program (6974)
