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Headaches : Several patients mention headaches in connection with thirst, potentially relating to hydration status

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doi: 10.4239/wjd.v1.i1.8

Animal studies demonstrated dose-dependent and treatment-duration-dependent increases in thyroid C-cell tumours in rodents treated with GLP-1 receptor agonists

In both animal models and human studies, the peptide has demonstrated an ability to lower food intake and reduce caloric consumption by acting on central satiety pathways and altering food-motivated behaviors[7]

The clinical outcomes data is robust and the benefit-risk profile, in appropriate patient populations, is well established