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However, the role of endogenous GLP-1 in the attenuation of reward-oriented behavior, and the essential domains of the mesolimbic system mediating these beneficial effects, are largely unknown

Participants experienced an average weight loss of 12-24% over 48 weeks

Simple Comparison between upcoming Monthly GLP-1s: By Amgen and Pfizer The Monthly Obesity Treatment Race Is Heating Up The next wave of obesity pharmacotherapy may not be about achieving greater efficacy aloneit may also be about achieving it with less frequent dosing

Each session does not need to be long

At present, obesity prevalence is predicted to rise to impact about one in four of the world's population in 2035

Conclusions GLP-1 agonists are associated with significant pancreatitis risk which increases with larger cumulative doses.