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Most semaglutide users experience their first side effects within 24 to 48 hours of the initial injection, though timing varies by individual metabolism and dose escalation

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no treatment with obesity medication (OM) for reducing weight and improving cardiometabolic risk factors among adults with obesity or overweight

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It is used alone or with other medications toimprove blood glucose (sugar) levels for people with Type 2 Diabetes

In this review, we discuss the clinical trials, efficacy, United States FDA-approved indication, contraindications, and serious side effects of different classes of drugs, including lipase inhibitors, GLP-1 agonists, leptin analogs, and MC4R agonists.