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Effects gradually diminish as levels drop over this period

Le, Each person is unique

The GLP-1R and GIPR pathways both converge on beta cell function through incretin signaling, and retatrutide provides a tool to study the amplified incretin response that occurs when both receptors are activated simultaneously

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This represents a key limitation of our study, as there may be variations in clinical outcomes and tolerance across the dose spectrum that our analysis could not detect