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Alter the hunger and fullness signals the brain receives

How do GLP-1 medications improve blood sugar levels in people without diabetes

Based on current evidence, GLP-1RAs are not recommended as first-line therapy for type 2 diabetic patients at high risk for colorectal cancer [47]

Due to the overlapping effects of glucagon and GLP-1 in eliciting food intake reductions, co-administration in humans synergistically reduces food intake thus allowing for lower-dosing of GLP-1 [28]

On the other hand, Timper et al

Aesthetically, the loss of muscle can reveal or worsen skin laxity, leading to concerns about hollowing in the face and changes in body contour, often described by patients as Ozempic face