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Clemens KK, Woodward M, Neal B, Zinman B (2020) Sex disparities in cardiovascular outcome trials of populations with diabetes: a systematic review and meta-analysis

These findings indicated that TGF-1 + IL-1 was sufficient to induce fibroblast activation by activating NLRP3 inflammasome, but insufficient to cause NLRP3/caspase-1/GSDMD-mediated fibroblast pyroptosis, while the underlying mechanism remains to be further explored

However, direct comparisons across these studies are limited by differences in design, patient selection, and follow-up duration

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Comparative effectiveness of sodium-glucose cotransporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors in improvement of fatty liver index in patients with type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver disease: A retrospective nationwide claims database study in Japan