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Long-term adherence is essential to realizing the full therapeutic potential of GLP-1s, yet behavioral factors (such as reaching personal weight goals or perceived social stigma) and systemic issues (like high out-of-pocket costs and fragmented care) disproportionately affect obesity patients

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Combination strategies (GLP-1 + BAT activator) may preserve lean mass, enhance adherence, and amplify CV/metabolic benefits
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