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evaluate the translational evidence supporting GLP-1RAs as candidate disease-modifying therapies for neurodegenerative diseases in this installment to the JCIs Review

Head-to-head post-registration trial or a real-world data study would be helpful

It helps curb cravings, ease bloat, and naturally doubles GLP-1 levels

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Method The PubMed (MEDLINE), EMBASE, Cochrane Library, and ClinicalTrials.gov databases were searched from the establishment of the database to December 24, 2022

Larger studies with standardized treatment approaches and strict lifestyle modification monitoring are needed to confirm these findings.