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Indeed, continuous exenatide exposure once weekly elicited a greater response than did short-acting exenatide, improving glycemic and lipids controls and lipoprotein metabolism, and decreasing systemic inflammation

Secretion of Exe4 peptide via gene knock-in in Hepa1-6 cells To achieve sustained Exe4 secretion, we targeted the Albumin ( Alb ) locus due to its hepatocyte-specific high expression levels, ensuring robust expression of the integrated scExe4 gene 9,33,34

During acute inflammation caused by A build-up, microglia phagocytose A and protect neurons from A toxicity (47)

The goal is to gradually reduce sympathetic nervous system activation and allow the parasympathetic system to take over

Acknowledgements This work was supported by grants from the National Natural Science Foundation of China to YL (No

[DOI] [PMC free article] [PubMed] [Google Scholar] 97.Maekawa R, Ogata H, Murase M, Harada N, Suzuki K, et al
