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Benchmarking against SUSTAIN-6 and SURPASS-CVOT In the emulation of SUSTAIN-6 comparing semaglutide to sitagliptin, a proxy for placebo, in patients at moderate and high cardiovascular risk (Table 2 and Supplementary Table 19), the hazard ratio (HR) for the primary endpoint was 0.68 (95% confidence interval (CI) 0.600.77) compared to the trial estimate of HR 0.74 (95% CI 0.58 to 0.95)

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How long does tirzepatide take to start working for weight loss

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Side effects and tolerability: Troy carefully evaluates how each medication may impact you and whether you might experience side effects

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And if you ever feel unsure or need reassurance, our clinical team is always here to listen and guide you forward. Ayesha Bashir , myBMI weight loss expert Thyroid-related side effects Thyroid-related side effects with Mounjaro are rare but are included as a safety warning because of findings seen in animal studies

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Maintenance dose Once you reach the desired results for ongoing weight loss or glycemic control, the dosage you are on is typically continued as a maintenance dose

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Sublingual drops and troches Sublingual tirzepatide dissolves under the tongue

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