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Dose level The clearest risk factor is dose

If nausea becomes unbearable, speak with a healthcare provider about meal timing or anti-nausea strategies rather than stopping the medication

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However, staying well hydrated is important because nausea, vomiting, or reduced fluid intake may contribute to dehydration, which can increase UTI risk

ADU selectively binds to A fibrils and soluble oligomers, which reduced amyloid plaques in a dose-dependent and time-dependent manner (63)

According to the SmPC , gastrointestinal adverse reactions are most frequent during treatment initiation and dose escalation, and tend to diminish over time