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Tirzepatide can cause modest increases in heart rate and, in some cases, changes in blood pressure during dose escalation

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Common side effects may include nausea, diarrhea and constipation

[DOI] [PubMed] [Google Scholar] 33.Mercer J, Lipscomb J, Lipscomb J et al

Future studies with larger datasets may clarify whether specific SNPs disproportionately drive observed effects or if subtle pleiotropic pathways exist