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GLP-1 receptor agonists (semaglutide, liraglutide, tirzepatide) act on the brain as well as the gut, and a 2026 real-world cohort study from Kamel-Abusalha et a

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Long-term adherence is essential to realizing the full therapeutic potential of GLP-1s, yet behavioral factors (such as reaching personal weight goals or perceived social stigma) and systemic issues (like high out-of-pocket costs and fragmented care) disproportionately affect obesity patients