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Description
It was reported that small molecule GLP-1RA could reduce chronic neuropathic pain and exert neuroprotective effects by improving synaptic plasticity and ameliorating neuronal death (28, 29)
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In patients with T2DM, where islet neogenesis and -cell replication are normal, increased apoptosis is the main cause of the decrease in their -cell numbers, so preventing -cell apoptosis may become an effective means of treating T2DM ( GLP-1 has a beneficial effect on -cell function by promoting -cell proliferation and neogenesis and reducing apoptosis (Zheng et al., 2022)

WEGOVY (semaglutide) prescribing information

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Hot flashes are sudden feelings of warmth, which are usually most intense over the face, neck and chest