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Comorbidities specific to OSA such as hypertension, hyperlipidemia, diabetes, cardiovascular disease, chronic obstructive pulmonary disease (COPD), depression, gastroesophageal reflux disease, metabolic disorders, somnolence, and stroke were identified using appropriate ICD-10 codes

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In clinical trials, oral semaglutide has demonstrated substantial dose-dependent lowering of both glycated haemoglobin (HbA 1c ) and body weight [15,16,17], with a safety profile in line with other GLP-1RAs [15, 18]

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Se realiz una bsqueda electrnica en el motor de bsqueda PubMed con trminos MeSH Diabetes Mellitus, Hyperglycemia, Diabetes Complications, Hypoglycemic Agents, Glucagon-Like Peptide-1 Receptor Agonists, Glycoside Hydrolase Inhibitors, Acarbose, Metformin, Dipeptidyl-Peptidase IV Inhibitors, Sodium-Glucose Transporter 2 Inhibitors, Drug-Related Side Effects and Adverse Reactions, Gastrointestinal Diseases, Gastroparesis, Gastric Emptying, Dysbiosis, Gastrointestinal Microbiome, Microbiota, Constipation, Diarrhea, Nausea, Vomiting, Gastrointestinal Agents

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These results are highly comparable to the efficacy of the established weekly injection

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