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Respondents reported a strong desire to reduce the pill burden associated with treatment, or to be off medication entirely, for treatments to help resume normal living, such as the ability to eat without restrictions, for treatments with fewer unpleasant side effects (i.e., weight gain, hypoglycemia, gastrointestinal side effects) and which are less physically invasive (i.e., do not require an injection) and for treatments which can normalize/stabilize blood glucose levels, and improve hemoglobin A1c

The most common side effects were stomach-related issues like nausea, vomiting, constipation, and diarrhoea

For people dealing with resistance in advanced disease, newer endocrine approaches and targeted combinations may matter more than a simple switch from one pill to another

A., Odeh, Y

Wuttke, S., Lismont, M., Escudero, A., Rungtaweevoranit, B

Nevertheless, evidence regarding its effects on muscle mass in the absence of exercise remains inconclusive [50]