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There have also been anecdotal reports of insomnia as a side effect, although the drugs manufacturer, Novo Nordisk, does not list it as a known adverse effect

However, medication is typically only used if lifestyle changes aren't effective or if there's an underlying heart condition

Safety Considerations When Combining Peptides Combining sermorelin and semaglutide introduces overlapping metabolic effects that require medical supervision
Diabetologia 28: 412419

Are All GLP-1 Drugs the Same in Helping with Weight Loss