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Note that the percentage range (abscissa) varies

Dosing is gradual by design

But while these drugs can be highly effective at suppressing appetite and accelerating weight loss, they also introduce new challenges that many people dont anticipate

51 One significant challenge is the high rate of gastrointestinal adverse events associated with these compounds, which may be related to their pharmacokinetic properties and direct gastrointestinal irritation

But the introduction of new oral drugs raises a lot of new questions as well, Cavender says

The expansion aims to produce injectables for obese patients and other serious chronic diseases