glp-1 ras mechanism and the kidney: from physiology to pharmacology and outcomes in diabetes GLP-1 RA education

[DOI] [PMC free article] [PubMed] [Google Scholar] 124

Sciwind Biosciences 8.1.10

After we eat, GLP-1 is released from the gut and tells the brain, Youre satiated. It also helps the pancreas release insulin, slows down how quickly food leaves the stomach, and reduces glucagon (a hormone that raises blood sugar)

doi: 10.1185/030079905x75078

Miller PE, Pawar S, Vaccaro B, McCullough M, Rao P, Ghosh R, Warier P, Desai NR, Ahmad T

Conclusion and perspective GLP-1R-independent signaling of GLP-1, its intra-islet axis, and its once-thought inactive metabolites, all represent new important additions to our understanding of this peptide in health and disease