comparing cardiovascular and kidney outcomes with tirzepatide vs. glp-1 agonists Comparative effectiveness of versus receptor on cardiovascular–kidney–metabolic stage progression: a real-world cohort study comparing cardiovascular and kidney outcomes
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doi:10.1378/chest.125.2_suppl.52S

GLP-1R knockout mice exhibit reduced responses to sweeteners, confirming their key role in sweet perception, as well as increased sensitivity to monosodium glutamate (MSG), suggesting GLP-1 may inhibit umami taste as well (65)
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