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Semaglutide does more than support weight lossclinical evidence shows it reduces LDL cholesterol and triglycerides while raising HDL, lowering heart disease risk in patients with obesity and metabolic dysfunction

Novo Nordisk and Eli Lilly's GLP-1s offer big health benefits and are cost-effective at current US prices, but affordability remains an issue.

GLP-1 medications peri-menopause can increase muscle and bone loss in women

David Lassen, vice president of pharmacy clinical services, and Marci Chodroff, vice president and medical director at Prime Therapeutics, share more about the latest GLP-1 insights from ongoing research

Palpitations / reflex tachycardia Fatigue Less Common Side Effects Nausea, abdominal pain Sleep disturbances Muscle cramps or joint pain Gingival hyperplasia (gum overgrowth, rare but possible with chronic use) Serious (but Rare) Side Effects Severe hypotension Arrhythmias (very rare) Allergic reactions (rash, itching, swelling) Liver dysfunction (rare, but check if jaundice or dark urine develops) Key Point for Patients Most frequent complaint = ankle edema

Ulcerations, which were difficult to heal, occurred in 5 of 7 children