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Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions.

Bloating is a common side effect of GLP-1 medications affecting digestion and gastric emptying

The US Food and Drug Administration approveddrugmaker Novo Nordisks application to add cardiovascular benefits to the medicines label, making it the first weight-loss drug to also be cleared to reduce the risk of heart attack, stroke or heart-related death in people at higher risk of these conditions.

Are they even remotely realistic?

It is prudent to reduce doses in obese patients.
