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the solution of Preparation 27 from Step 1 and the Preparation 28 and PyOxim streams are pumped into a mixer and at the outlet of the mixer the DIEA is combined and the mixture is pumped through another mixer and through a plug flow reactor for a 2 h residence time in a 20C constant temperature bath
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Increasing the endogenous production of GLP-1 through increasing the L-cells may be an effective therapeutic approach to managing T2DM
