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No significant drug interactions have been identified between GLP-1 receptor agonists and standard autoimmune medications including methotrexate, biologics (TNF inhibitors, IL-6 inhibitors), JAK inhibitors, or hydroxychloroquine
Some theories claim that estrogens directly act through dorsal raphe nuclei 5-HT neurons to inhibit binge eating and that impaired brain 5-HT signaling is an important component of binge eating development ( 15 - 18 )
doi: 10.7759/cureus.29262
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Clinical Rationale for Early AOM Intervention Traditional obesity management often follows a fixed-duration behavioral therapy (BT) approach before considering medication, yet mounting evidence suggests this may not be optimal for many patients
