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2022 Sep 22;387(12):1063-1074

N Engl J Med 2021;384:9891002.ArticlePubMed 18

The shift supports a move toward beverages that support emotional and metabolic health

SURMOUNT-MMO: A Phase 3, Randomized, Double-blind, Placebo-Controlled Study to Investigate the Effect of Tirzepatide on the Reduction of Morbidity and Mortality in Adults With Obesity

Combination or staged GLP-1 with nutrition therapy Given the existing adherence and cost challenges of GLP-1s coupled with significant weight regain after discontinuation, combination or staged therapy with intensive lifestyle management could promote greater efficacy, cost-effectiveness, and equitable obesity care [3,18,222,[271], [272], [273]]

These medications act on hormone pathways involved in appetite signaling and metabolic regulation