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GLP-1 medications like Semaglutide (Ozempic, Wegovy) and Tirzepatide (Mounjaro) work by mimicking hormones that regulate appetite and blood sugar

The American College of Cardiology/American Heart Association/The Obesity Society guidelines emphasize individualized treatment plans incorporating lifestyle modification, behavioral therapy, pharmacotherapy when appropriate, and metabolic/bariatric surgery for eligible patients

In addition to enhancing insulin secretion, binding to these receptors and downstream signaling slow gastric emptying and reduce appetite, leading to weight loss

Other oral GLP-1 drugs, like Orforglipron, are in clinical trials but not yet available

Women under 40 Premenopausal women on GLP-1 medications face hair loss primarily from telogen effluvium and nutritional depletion