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Patients shed as much as 15% of their body weight within one year

(4) We further extracted the SNPs with a correlation less than 5 10 4 from the HbA1c dataset and excluded SNPs to reduce the influence of LD-induced bias using the 1000 Genomes European reference panel (r2 = 0.01

JCI Insight 3(18):e121495

Patients are encouraged to report any suspected side effects to the MHRA Yellow Card Scheme, which helps monitor the safety of medicines in the UK

In total, 99.7% of the patients completed the trial and the vital status was known at the end of the trial for 100%

Weight loss can have secondary cardiovascular benefits, but new research suggests GLP-1s may have a direct impact on heart health, too, with anti-obesity drugs among the American College of Cardiologys top five trends in cardiovascular medicine for 2025