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Eligible participants had a body mass index (BMI) 30 kg/m (obesity) or a BMI 27 kg/m with obesity-related comorbidities, such as hypertension or hyperlipidemia (overweight with comorbidities)

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Both TZP and TZP+FcLep groups exhibited a marked reduction in serum insulin levels under ad libitum feeding conditions, indicating improved insulin resistance (Fig

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Generic versions of these medications do not yet exist, though patents will expire within the next decade

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