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Moreover, GLP-1 RAs have been shown to protect against oxidative stress, cellular senescence and chronic inflammation, which are widely accepted as the major risk factors of aging

Lilly Zepbound / Mounjaro (tirzepatide) ~21% mean weight loss at ~72 weeks (top dose) Clear superiority vs Wegovy Growing long-term durability data Takeaway: Zepbound remains the benchmark every obesity drug must beat or meaningfully out-differentiate

A recent study tracked self-reported GLP-1 side effects among Reddit users and found several overlooked side effects like chills and hot flashes linked to weight loss medications like Ozempic and Mounjaro.