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Given the increasing use of GLP-1 RAs, larger-scale evaluations of their perioperative risks are needed

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Testing these pathways reveals whether you are a responder, partial responder, or require protocol optimization

2 GLP-1 AND GLP-1/GIP RECEPTOR AGONIST MEDICATIONS Endogenous incretin hormones play a vital role in maintaining homeostasis with the regulation of insulin and glucose

GLP-1 is secreted by intestinal L cells and by preproglucagon neurons in the nucleus tractus solitarius, which project widely to areas governing cognition, motor control, reward, autonomic regulation, and energy homeostasis (45, 46)