glp 1 agonist liraglutide Study shows results in increased insulin sensitivity independent of weight loss GLP-1 agonists have transformed diabetes

GLP-1 side effects All of the GLP-1s went through an extensive clinical review and approval process and are considered generally safe medications

That being said only 4.1 % of patients stopped the 4mg dose which is less than the placebo arm

Crajoinas RO, Polidoro JZ, Carneiro de Morais CP, Castelo-Branco RC, Girardi AC

In people with T2D, a phase 1b study did not demonstrate improvement in HbA1c, however there was a placebo-adjusted WL of 8.5% after 12 weeks (Table 3)

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

GLP-1 For Weight Loss: Is It Safe