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Of note, the phase 1 and 2 RCTs included in this meta-analysis had short follow-ups, and the weight curves indicate that a plateau in weight loss was not reached, suggesting that greater percentages of weight loss may be observed in studies with longer follow-ups

N Engl J Med 381(9): 841 851 Fudim M, White J, Pagidipati NJ, Lokhnygina Y, Wainstein J, Murin J, Iqbal N, hman P, Lopes RD, Reicher B, Holman RR, Hernandez AF, Mentz RJ (2019) Effect of Once-Weekly Exenatide in Patients With Type 2 Diabetes Mellitus With and Without Heart Failure and Heart Failure-Related Outcomes: Insights From the EXSCEL Trial

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