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Dysregulation of Bgn expression can result in a wide range of clinical conditions such as metabolic disorder, inflammatory disorder, musculoskeletal defects, and malignancies ( Mitogen-activated protein kinase activated protein kinase 3 is a member of the Mapk signaling pathway family ( Bgn gene can upregulate p38Mapk ( Conclusion In summary, we screened out the key differential genes that affect feeding behavior after GLP-1R activation through bioinformatics analysis