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For a patient on metformin and insulin degludec who cannot use GLP-1 receptor agonists due to pancreatitis history, add an SGLT2 inhibitor with proven cardio...

Methods Blood was drawn from 24 subjects (14 male, 10 female, age: 50.77.36years, BMI: 26.643.38kg/m2, GHbA1c: 7.000.74%) with drug-nave T2D at 0 and 120min following a standard mixed meal for the measurements of active GLP-1, NO and NOS

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Glucagon-like peptide-1 receptor agonists also lead to satiety and appetite reduction through action on the brains appetite regulation centers, leading to weight loss in obese patients